Type VI Secretion Systems (T6SSs) are widespread in bacteria and can dictate the development and organisation of polymicrobial ecosystems by mediating contact dependent killing.In Neisseria species, including Neisseria cinerea a commensal of the human respiratory tract, interbacterial contacts are mediated by Type four pili (Tfp) which promote form
Cross-sectional evaluation of health resource use in patients with functional neurological disorders referred to a tertiary neuroscience centre
Introduction Functional neurological disorder (FND) is a common cause of referral to neurology services.FND has been shown to lead to significant healthcare resource use and is associated with significant disability, comorbidity and distress.This leads to substantial direct, indirect and intangible costs to the patient and society.Methods We recrui
TRAIL pathway is associated with inhibition of colon cancer by protopanaxadiol
Among important components of American ginseng, protopanaxadiol (PPD) showed more active anticancer potential than other triterpenoid saponins.In this study, we determined the in vivo effects of PPD in a mouse cancer model first.Then, using human colorectal cancer cell lines, we observed significant cancer cell growth Curling - Clothing - Mens inhi
Controversial Funerary Art in British Empire War Cemeteries (1917-1922)
Cemeteries are places of remembrance and meditation, but also spaces for artistic expression.The shape of funerary monuments can be Dog Bowl defined by the deceased themselves before their death or by their relatives after their death, and reflect their life and values.In the aftermath of the First World War, this choice was not made available to t
The Challenges Associated With Connectivity in Ecosystem Processes
Developing a framework to quantify the transformation, sequestration or Salmon connectivity of energy and matter across habitats is one of the most significant challenges faced by ecologists and resource managers today.However, there are significant challenges associated with quantifying the ecosystem processes that connect and interact across habi